BRIAN R. ESTVANDER
763 Cherry Creek Drive
Grayslake, IL 60030
Brian@Estvander.com
630-881-2526 (Cell)

PUBLICATIONS
Krueger K.M., Estvander B.R., Miller T.R., Baranowski J.L., Sharma R., Hancock A.A., Esbenshade T.A., Species-dependent pharmacological classification of histamine H3 receptor ligands determined by amino acids 119 and 122 in TM3. Journal of Pharmacological Experimental Therapeutics.

Miller T.R., Baranowski J.L.,
Estvander B.R., Witte D.G., Carr T.L., Manelli A.M., Krueger K.M., Cowart M.D., Brioni J.D., Esbenshade T.A. "A robust and high-capcity [(35)S]GTPgammaS binding assay for determining antagonist and inverse agonist pharmacological parameters of histamine H(3) receptor ligands" Assay Drug Development Technology, (2008), 6(3), 339-349.

Bongers G., Krueger K.M., Miller T.R., Baranowski J.L.,
Estvander B.R., Witte D.G., Strakhova M.I., van Meer P., Bakker R.A., Cowart M.D., Hancok A.A., Esbenshade T.A., Leurs R. "An 80-amino acid deletion in the third intracellular loop of a naturally occurring human histamine H3 isoform confers pharmacological differences and constitutive activity" Journal of Pharmacological Experimental Therapeutics, (2007), 323(3), 888-898.

Esbenshade T.A.,
Estvander B.R., Miller T.R., Baranowski J.L., Sharma R., Hancock A.A., Krueger K.M. "Pharmacological classification of histamine H3 receptor agents across species is attributable to transmembrane 3 sequence differences" Inflammation Research, 56, Supplement 1(2007), S45-6.

Esbenshade T.A., Krueger K.M., Yao B.B., Witte D.G.,
Estvander B.R., Baranowski J.L., Miller T.R., Hancock A.A. "Differences in pharmacological properties of histamine H3 receptor agonists and antagonists revealed at two human H3 receptor Isoforms" Inflammation Research, 55, Supplement 1 (2006) S45-6.

ABSTRACTS
Esbenshade T.A., Miller T.R., Baranowski J.L., Estvander B.R., Carr T.L., Strakhova M.I., Cowart M., Hancock A.A., Krueger K.M., Brioni J. (2006). Isoform dependent differences in histamine H3 receptor constitutive activity revealed by human H3(445) and H3(365). ASPET.

Esbenshade T.A., Miller T.R., Baranowski J.L.,
Estvander B.R., Carr T.L., Strakhova M.I., Cowart M.D., Hancock A.A., Krueger K.M., Brioni J. (2006). Differences in histamine H3 receptor constitutive activity revealed by human H3(445) and H3(365) receptor Isoforms. European Histamine Research Society.

Miller T.R., Baranowski J.L.,
Estvander B.R., Carr T.L., Strakhova M.I., Cowart M., Esbenshade T.A., Hancock A.A., and Krueger K.M. (2006). Differing degrees of histamine H3 receptor constitutive activity by human H3(445) and H3(365) receptor Isoforms. Society for Neuroscience Annual Meeting.

Estvander, B.R., Stamper, G., Pereda-Lopez, A., Lake, M., Hancock, A.A., Chiu, M., Esbenshade, T.A., and Krueger, K.M. Solubilization of the histamine H3 receptor and the assessment of activity utilizing a radioligand binding assay. (2005). Abbott Technology Exchange, Abbott Laboratories, Abbott Park.

Krueger, K.M.,
Estvander, B.R., Miller, T.R., Baranowski, J.L., Sharma, R., Hancock, A.A., and Esbenshade, T.A. Species-dependent pharmacological classification of histamine H3 receptor ligands determined by amino acids 119 and 122 in TM3. (2005). Gordan Research Conference on Second Messengers and Protein Phosphorylation, University of New England, Biddeford, ME.

Esbenshade, T.A., Krueger, K.M., Yao, B.B., Witte, D.G.,
Estvander, B.R., Baranowski, J.L., Miller, T.R., and Hancock, A.A. (2005) Differences in Pharmacological Properties of Histamine H3 Receptor Agonists and Antagonists Revealed at Two Human H3 Receptor Isoforms. European Histamine Research Society, Bled Slovenia.

Miller, T.R, Baranowski, J.L.,
Estvander, B.R., Cowart, M., Esbenshade, T.A., Hancock, A.A., Krueger, K.M. (2005) Development and Application of Robust [35S]GTP S Binding Assays for Pharmacological Characterization of Histamine H3 Receptor Ligands. Society for Neuroscience Annual Meeting.

El Kouhen, R. Bianchi, B.R.,
Estvander, B.R., Surowy, C.S., Jarvis, M.F., Faltynek, C.R. (2003) Correlation between phosphorylation and sensitization of the VR1 receptor. Society for Neuroscience Annual Meeting.

Estvander, B.R., Gasser, K. W. (2001) Regulation and role of rat pancreatic protein kinase C isoforms in the Erk signaling pathway and exocytosis. Biological Research Symposium, Northern Illinois Univeristy.